陈培剑;李鲁新;丁明璐;宋旭东;初彦辉;

• 1:牡丹江医学院医药研究中心

摘要(Abstract)：

近年来,糖尿病在我国已成为严重的代谢性疾病之一。糖尿病引发的并发症是致死的重要因素,威胁着人类的生命健康。糖尿病性心肌病(Diabetic cardiomyopathy,DCM)是糖尿病并发症之一,其特点是心肌纤维化、心脏功能不全等。目前已经有了研究探索其分子机制、结构和功能的变化,以及用于治疗和预防DCM的治疗的方法,据一些研究发现非编码RNA参与氧化应激、心肌纤维化、RAS系统的调控等方面进而影响糖尿病性心肌病的发展。本综述选取了较典型的非编码RNA在糖尿病性心肌病中的最新研究进展,为后续疾病诊疗的发展提供有效的理论依据。

关键词(KeyWords)： 糖尿病性心肌病;非编码RNA;微小RNA;长链非编码RNA

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 陈培剑;李鲁新;丁明璐;宋旭东;初彦辉;

Email:

DOI: 10.13799/j.cnki.mdjyxyxb.2020.06.030

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