树突细胞的研究现状
朱咪咪;孔梦影;别福鑫;张召弟;于冰;郭燕;张丽;
摘要(Abstract):
树突状细胞(dendritic cell,DC)是目前发现最强的抗原递呈细胞。分布于体内各个组织和器官内,根据其形态和功能不同,主要将其分为2大亚型,即髓系和淋巴系。随着近年来深入的研究,人们逐渐认识到两种起源的DC在功能及分布上有很大的不同,在免疫系统中发挥重要功能,具有双向调节作用,不但可以激活免疫反应而且参与机体的免疫耐受,在炎症反应、抗感染、自身免疫疾病、抗肿瘤等病理生理过程中有着重要的免调节作用。为此,我们关于树突状细胞生物学特征及功能的研究进展进行阐述。
关键词(KeyWords): 树突状细胞;分子生物学;免疫
基金项目(Foundation): 黑龙江省卫生计生委科研课题(2016-389)
作者(Author): 朱咪咪;孔梦影;别福鑫;张召弟;于冰;郭燕;张丽;
Email:
DOI: 10.13799/j.cnki.mdjyxyxb.2018.02.034
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