麻醉深度与病人术后认知功能障碍的相关性研究
李希才;许奎斌;崔刚;魏铁钢;柴富;赵新杰;刘玉平;张晓红;区继岩;周鑫;韩庆强;
摘要(Abstract)：
目的:观察麻醉深度与早期术后认知功能障碍是否有关联。方法:选择全麻下择期行胃部肿瘤切除手术的患者40例。将患者随机分为深麻醉组和浅麻醉组,将所有被测试者于术前1d使用韦氏成人智力量表进行筛查测试,得分大于23分为合格者可进行后面的测试。分别在术后1d、术后3d和术后5d对符合条件的患者进行认知功能测验;为了减少学习效应引起的误差,4次测定使用A、B量表交替来进行。结果:与术前相比,深麻醉组和浅麻醉组术后1d和5d的WAIS评分差异具有极显著性差异(P<0.01),两组间及两组内各时点比较差异具有极显著性差异(P<0.01),各次项组间比较差异无统计学意义(P>0.05)。结论:全麻术中维持BIS值在30~40镇静深度对病人早期术后认知功能影响小,术后认知功能障碍发生率低。
关键词(KeyWords)： 麻醉深度;脑电双频指数;韦氏成人智力量表;认知功能障碍
基金项目(Foundation):
作者(Author): 李希才;许奎斌;崔刚;魏铁钢;柴富;赵新杰;刘玉平;张晓红;区继岩;周鑫;韩庆强;
Email:
DOI: 10.13799/j.cnki.mdjyxyxb.2014.04.045
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