微量清蛋白尿对冠心病患者发生心血管事件的影响
杜英;兰军;涂昌;程飞;陈杰民;钟耀棠;
摘要(Abstract):
目的探讨冠心病患者微量清蛋白尿(MAU)的出现对发生心血管事件的影响。方法入选该院冠心病患者共50例,根据尿清蛋白排泄率(UAER)分为MAU组(UAER 30300mg/d,n=25)和对照组(UAER<30mg/d,n=25),并比较分析其相关危险因素。随访12个月后比较分析其合并心血管事件(心力衰竭、急性冠脉综合征、脑卒中)的发生。结果MAU组的微量尿清蛋白水平显著高于对照组,差异有统计学意义(P<0.001)。MAU组的急性冠脉综合征、心力衰竭、脑卒中的发病率分别为68%,48%,36%;对照组的急性冠脉综合征、心力衰竭、脑卒中的发病率分别为36%,20%,8%。两组相关危险因素无明显差别,而MAU组心心血管事件(急性冠脉综合征、心力衰竭、脑卒中)的发病率显著高于对照组(P<0.05)。结论微量清蛋白尿可以作为预测冠心病患者发生心血管事件(心力衰竭、急性冠脉综合征、脑卒中)的危险因素之一。
关键词(KeyWords): 微量清蛋白尿;冠心病;心血管事件
基金项目(Foundation):
作者(Authors): 杜英;兰军;涂昌;程飞;陈杰民;钟耀棠;
DOI: 10.13799/j.cnki.mdjyxyxb.2016.03.018
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