脉胳宁注射液扩血管作用机制的研究Study on Vasodilating Mechanism Injetion (Radix Scrophulariae, Radix Achyranthis Bidentatae, etc.)
冯芹喜,郎凤兰,张志国,杨履艳,关利新
摘要(Abstract):
用离休兔胸主动脉为标本,以维拉帕米(Ver)为对照药,观察了脉胳宁注射液对血管平滑肌的作用。结果,脉胳宁注射液对NEKCL及C2CL2收缩兔胸注动脉条的量效曲线呈非竞争性拮抗作用,并能明显抑制NE引起的主动脉条依赖于细胞外钙的收缩,其作用性质与Ver相似。提示脉胳宁注射液的扩血管作用机制可能与其对钙通道的阻滞作用有关。
关键词(KeyWords): 脉胳宁;血管舒张药;主动脉
基金项目(Foundation):
作者(Author): 冯芹喜,郎凤兰,张志国,杨履艳,关利新
DOI: 10.13799/j.cnki.mdjyxyxb.1998.01.001
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