安锦丹;李志强;曹永;颜彬;展涛;

• 1:牡丹江医学院病理教研室

摘要(Abstract)：

目的:探讨卵巢浆液性和黏液性肿瘤中黏蛋白MUC2的表达与临床病理特征的相关性。方法:免疫组织化学S-P法检测90例卵巢浆液性和黏液性肿瘤的黏蛋白MUC2的表达。结果:(1)交界性与恶性卵巢肿瘤中黏蛋白MUC1的表达阳性率明显高于良性肿瘤,差异有显著性(P=0.0001);黏蛋白MUC1与WHO病理分级、FIGO临床分期、大网转移显著相关(P<0.05)。(2)黏蛋白MUC2与组织学类型、WHO病理分级相关(P<0.05)。结论:黏蛋白MUC2与恶性卵巢浆液性和黏液性肿瘤的浸润、转移相关。

关键词(KeyWords)： 卵巢上皮性肿瘤;黏蛋白;MUC2;免疫组织化学

Abstract:

Keywords:

基金项目(Foundation): 牡丹江医学院科学研究项目(2011-04)

作者(Authors): 安锦丹;李志强;曹永;颜彬;展涛;

DOI: 10.13799/j.cnki.mdjyxyxb.2011.06.039

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