MRI在急性弥漫性轴索损伤中的诊断价值
王斌;李军;陈伟;王金华;刘振堂;
摘要(Abstract)：
目的:探讨磁共振梯度回波T2成像(T2*weighted gradient-recalled-echo,T2*GRE)联合扩散加权成像(diffusion weighted imaging,DWI)在急性弥漫性轴索损伤(diffuse axonal injury,DAI)中的诊断价值。方法:回顾性分析38例急性弥漫性轴索损伤(DAI)患者的头颅MRI检查,比较MRI各序列间的检测灵敏度,并将检出的病灶数与患者入院格拉斯哥昏迷评分(GCS)行相关性分析。结果:T1WI共检出DAI病灶49个,T2WI检出78个、FLAIR检出139个,T2*GRE检出142个,DWI检出212个,T2*GRE联合DWI检出245个。DWI对非出血性DAI病灶的检出率最高,与其它序列的差异有统计学意义(p<0.05)。T2*GRE对出血性DAI病灶的检出率最高,与其它序列的差异有统计学意义(p<0.05)。联合T2*GRE及DWI两种技术对DAI病灶的检出率均显著高于单独应用DWI(p<0.05)或T2*GRE(p<0.05)。联合T2*GRE及DWI两种技术检出的病灶数目与患者入院GCS呈高度负相关(r=-0.796,P<0.01)。结论:T2*GRE和DWI序列联合应用大大提高DAI病灶的检出率,为临床早期诊断提供更加可靠地影像学依据,应作为MRI检查DAI的常规序列。
关键词(KeyWords)： 弥漫性轴索损伤;梯度回波T2*成像;扩散加权成像;格拉斯哥昏迷评分
基金项目(Foundation): 东莞市医疗卫生科技计划项目(201210515023165)
作者(Authors): 王斌;李军;陈伟;王金华;刘振堂;
DOI: 10.13799/j.cnki.mdjyxyxb.2014.02.045
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