杨斯琪;许晓义;王翊豪;宋高臣;

• 1:牡丹江医学院

摘要(Abstract)：

肝癌即为肝脏的恶性肿瘤,也是当今时代高发疾病的一种难治性癌症,预后极差,对于肝癌的发病机制并不是很清楚,但是就目前为止对肝癌相关基因的研究来看,p53基因,KRAS基因,PTEN基因,CDK2基因,TLR2基因,β-catenin基因c-myc基因等多种基因突变都与肝癌的发生有关系,但是在研究方面上来看前三者更为重要些,因此本综述针对几个较为有价值的基因所发生突变的机制和靶向治疗进行一下阐述。

关键词(KeyWords)： 肝癌;基因;靶向治疗

Abstract:

Keywords:

基金项目(Foundation): 黑龙江省大学生创新创业训练计划项目(201610229071);; 黑龙江省中医药中青年科技攻关项目(2QG-056);; 牡丹江市科学技术计划项目(Z2015s0028);; 黑龙江省博士后科研启动金一等资助项目(LBH-Q15141)

作者(Authors): 杨斯琪;许晓义;王翊豪;宋高臣;

DOI: 10.13799/j.cnki.mdjyxyxb.2017.06.036

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