视黄醇结合蛋白4与冠心病的相关性探讨RELATIONSHIP BETWEEN RETIONL BINDING PROTEIN 4 AND CARDIOVASCULAR DISEASE
郭继芳;孔繁和;
摘要(Abstract)：
目的:探讨研究视黄醇结合蛋4(RPB4)与冠心病(CHD)的相关性。方法:选择100例研究对象,其中冠心病组60例和对照组40例,均采用酶联免疫吸附法(ELISA)测定血浆RPB4水平,测量身高,体重,腰臀比值(WHR),血压等,并采集记录相应生化数据:FPG、糖化血红蛋白(HbA1c)、总胆固醇(TC)、三酯酰甘油(TG)、血清高密度脂蛋白胆固醇(HDL-C)、血清低密度脂蛋白胆固醇(LDL-C)、超敏C反应蛋白(hs-CRP),应用统计软件进行统计检验。结果:冠心病组血浆RPB4水平明显高于正常对照组[(44.82±15.88),(36.60±12.20),P<0.05]。相关分析显示冠心病患者血清RBP4水平与WHR,SBP,TG,hs-CRP,FPG,HOMA-IR呈正相关。结论:血清RBP4与冠心病存在一定的相关性,可能与斑块稳定性有关,可作为预测斑块稳定性的血清标志物。
关键词(KeyWords)： 视黄醇结合蛋白4;冠心病;相关性
基金项目(Foundation):
作者(Authors): 郭继芳;孔繁和;
DOI: 10.13799/j.cnki.mdjyxyxb.2013.02.035
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