吗啡成瘾大鼠丘脑束旁核超微结构的改变CHANGES IN NEURONAL ULTRASTRUCTURE OF PF IN MORPHINE DEPENDENT RATS
岳辉;赵冬梅;关艳中;
摘要(Abstract)：
目的:观察吗啡成瘾大鼠束旁核超微结构的改变。方法:按逐日递增法背部皮下注射吗啡6d,制作成瘾模型,用电镜观察成瘾后大鼠束旁核超微结果。结果:吗啡成瘾组大鼠Pf神经元细胞核畸变明显,核表面出现形态不规则的切迹,细胞浆内线粒体空泡变性,突触膜融合,突触小泡消失,神经毯区髓鞘灶性崩解或裂解,轴突内线粒体絮状变。结论:吗啡成瘾严重损伤束旁核超微结构。
关键词(KeyWords)： 吗啡成瘾;大鼠;束旁核;超微结构
基金项目(Foundation):
作者(Authors): 岳辉;赵冬梅;关艳中;
DOI: 10.13799/j.cnki.mdjyxyxb.2011.02.055
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