替罗非班对急性心梗冠脉介入术后C反应蛋白的影响
张雪媛;赵莹;王媛媛;高凤敏;
摘要(Abstract)：
目的:观察应用替罗非班对急性心肌梗死行急诊冠脉介入的影响,观察C反应蛋白的变化,评价其对远期预后影响。方法:选择42例急性心梗并行急诊冠脉介入手术的患者,随机分为治疗组和对照组,治疗组在常规治疗心梗的基础上加替罗非班400mL,12mL/h。对照组常规应用抗心梗治疗。测量治疗前后两组病人血清C反应蛋白的含量,从而衡量病人心肌损伤影响。结果:治疗4周后,对照组C反应蛋白由9.5±0.7 mg/L降低至9.0±0.8mg/L,治疗组C反应蛋白由9.3±0.8mg/L降低至5.4±0.9mg/L,对照组内C反应蛋白降低不显著(P>0.05),无统计学意义,组间比较治疗后差别显著(P<0.01)。结论:替罗非班可以明显降低急性心肌梗死患者急诊介入手术后C反应蛋白水平,明显减少心肌损伤,改善患者预后。
关键词(KeyWords)： 替罗非班;急性心肌梗死;冠脉介入术;C反应蛋白
基金项目(Foundation): 牡丹江市科学技术局科研项目(g2010z0003)
作者(Authors): 张雪媛;赵莹;王媛媛;高凤敏;
DOI: 10.13799/j.cnki.mdjyxyxb.2012.01.032
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