吴晓文;余伟鹏;冼美兰;

• 1:汕头市潮阳区大峰医院呼吸内科

摘要(Abstract)：

目的研究无创正压通气联合布地奈德福莫特罗粉吸入剂治疗慢性阻塞性肺疾病急性加重(AECOPD)合并Ⅱ型呼吸衰竭的疗效。方法按标准纳入57例COPD合并Ⅱ型呼吸衰竭患者,按随机数字表法随机分成两组,对照组给予常规治疗及布地奈德福莫特罗粉吸入剂吸入,观察组在对照组的基础上给予无创正压通气治疗,动态观察两组患者通气、氧合、心率、呼吸频率等改善情况。结果观察组患者开始治疗2h后,呼吸困难相关临床症状明显好转,心率、呼吸频率显示下降,Pa CO2下降,Pa O2升高,比对照组显著改善,差异有统计学意义(P<0.05)。观察组在治疗72h后,预后改善情况均明显好于对照组,差异有统计学意义(P<0.05)。观察组病愈出院率较高,而插管率、病死率较低,住院时间较短,与对照组比较,差异有统计学意义(P<0.05)。结论布地奈德福莫特罗粉吸入剂联合无创正压通气治疗慢性阻塞性肺疾病急性加重合并Ⅱ型呼吸衰竭,可有效缓解临床症状,改善患者预后,安全有效。

关键词(KeyWords)： 慢性阻塞性肺疾病;Ⅱ型呼吸衰竭;无创正压通气;布地奈德福莫特罗粉吸入剂

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 吴晓文;余伟鹏;冼美兰;

DOI: 10.13799/j.cnki.mdjyxyxb.2015.03.004

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